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Efficacy and safety of pilocarpine for radiation-induced xerostomia in patients with head and neck cancer
CE Credit(s):
1
Member Price:
$5.00
Retail Price:
$40.00
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Open Tabs
Description:

JADA April 2016
Pilocarpine has been used widely in the treatment of dry mouth and glaucoma. In this review, the authors assessed the efficacy and safety of pilocarpine for patients with head and neck cancer who have radiation-induced xerostomia. The authors conducted a systematic search including meta-analyses and randomized controlled trials in the following databases: MEDLINE, Embase, Cochrane Library, and Science Citation Index Expanded. The primary outcome was the severity of xerostomia (measured using visual analog scale [VAS] scores). Adverse events were other outcomes of interest. The authors performed meta-analyses where appropriate. The authors used the Cochrane Collaboration’s tool for assessing risk of bias to assess the quality of the study.

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