Local anesthesia (LA) forms the backbone of pain control
techniques in dentistry. The receipt of a LA injection is, unfortunately, the
most traumatic part of the dental procedure for most patients. Trypanophobia
(fear of needles) is estimated to be present in ~10% of the world’s population.
Fainting during LA injection is, far and away, the most common medical emergency
encountered in dentistry. The ability to obtain profound pulpal anesthesia for
restorative dental procedures without injection will enable a dentist to provide
comfortable, safe and effective treatment to many needle-phobic persons who
previously avoided seeking dental care.
An intranasal local anesthetic mist – a combination of tetracaine HCl and
oxymetazoline – has been developed that provides pulpal anesthesia to the
maxillary non-molar teeth. In this program Dr. Malamed will discuss the problem
of needle-phobia as well as the development and efficacy of this new intranasal
local anesthetic mist.
- Name the five currently available dental local anesthetics and their
expected durations of action
- Describe the incidence of syncope as a medical emergency in dentistry as
it related to the problem of needle-phobia (trypanophobia)
- List the advantages of tetracaine HCL for use as an intranasal local
anesthetic mist and explain the rational for the inclusion of oxymetazoline.
- Discuss the results of the FDA Phase 2 and 3 adult clinical trials
comparing K305 to tetracaine and to placebo
- Discuss the results of the FDA 3 pediatric clinical trial comparing K305
This course is sponsored by St. Renatus, LLC.