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Do buffered local anesthetics provide more successful anesthesia than nonbuffered solutions in patients with pulpally involved teeth requiring dental therapy? (March 2019 Article 1)
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JADA March 2019

Background: The authors conducted a systematic review that addresses the following population,intervention, comparison, outcome question: “In adults requiring dental therapy with pulpally involved teeth, what is the comparative efficacy of buffered local anesthetics (LAs) compared with that of nonbuffered LAs in achieving anesthetic success?”.

Key Words: Buffering; sodium bicarbonate; alkalinization; adjusting pH; local anesthetic.

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