The path to oral cancer diagnosis involves the diagnosis and treatment of the cancer. The diagnosis of oral cancer involves the discussion of risk factors with the patient, a hands-on evaluation of radiographs, intraoral tissue, and the head and neck area. Once a suspicion is established of a lesion, the patient is referred for further evaluation by the treatment specialist. It is important to realize that the sooner a specious lesion if diagnosed and staged, the better the outcome. The lecture further covers the need for the general dentist and specialist to work together with post-treatment care.